Additional Study Information: Tomography (DOT), can help predict how well patients respond to a pre-surgical therapy. This imaging technique uses light to create 3D maps of the blood, fat, and water content of the breast. Based on these measurements taken over 2 time points during therapy (before and after), we will try to determine if this new imaging technique can use early measurements to predict the response of the tumor to the drug. If successful, this new imaging technique may allow a better way to customize therapy to each individual patient in order to optimize treatment.