Pilot study utilizing master regulator analysis to prioritize treatment of residual disease following neoadjuvant chemotherapy for breast cancer in patient-derived tumor xenografts
Study of using patient's residual tumor to develop a cancer model
Sponsor: Champions Oncology, SWOG
Enrolling: Male and Female Patients
IRB Number: AAAN9005
Contact: Kevin Kalinsky, MD, MS: 212-305-0190 / kk2693@cumc.columbia.edu
Additional Study Information: The purpose of this research study is to determine if using a piece of the patient's residual tumor to develop a model of her cancer in mice that lack an immune system (also called an immune-deficient mouse) could help in determining which additional drugs or compounds to which an individual breast tumor is sensitive. The tumor implanted in the mouse is called a patient-derived xenograft model or PDX model. We will also be measuring gene expression from the tumor specimen, collected at time of surgery, in order to select specific targeted medications to test in the PDX models.
This study is closed
Investigator
Kevin Kalinsky, MD, MS
Do You Qualify?
Do you have invasive breast cancer? Yes No
Have you received standard neoadjuvant chemotherapy for your breast cancer? Yes No
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Place Holder




For more information, please contact:
Kevin Kalinsky, MD, MS
kk2693@cumc.columbia.edu
212-305-0190