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RecruitMe Clinical Trial

Aspirin for Exercise in Multiple Sclerosis
ASPIRE: Aspirin for Exercise in Multiple Sclerosis
Sponsor:National Institute of Child Health and Human Development NCMRR
Enrolling:Male and Female Patients
Clinic Visits:3
Age Range:Between 18 and 65 years old
IRB Number:AAAS2529
U.S. Government ID:NCT03824938
Contact: Rachael Richards: 212-305-1485 / mscenter_neuro@cumc.columbia.edu
Additional Study Information:

ASPIRE is a clinical trial to investigate aspirin as a treatment to improve exercise performance in people with multiple sclerosis (MS) who experience overheating during exercise. Persons with multiple sclerosis benefit from exercise, but many avoid it because of exhaustion and overheating. This randomized controlled trial (RCT) tests aspirin as a method to increase time to exhaustion for persons with MS, through its antipyretic mechanism. Participants will be seen at our laboratory for maximal exercise tests on three separate days. At each session, they will be given one of three treatments: aspirin, acetaminophen (a drug that is anti-inflammatory but not antipyretic, thereby allowing for isolation of the antipyretic action of aspirin), and placebo. Primary outcome is increased time to exhaustion, secondary outcome is reduced body temperature increase during exercise.

Do You Qualify?
Is overheating during exercise an issue for you?YesNo
Have you ever had a stroke?YesNo
Do you currently use any antipyretics (fever reducers such as ibuprofen, naproxen, aspirin, acetaminophen) on a DAILY basis?YesNo
Have you ever suffered a significant head injury?YesNo
Do you have multiple sclerosis (MS)?YesNo
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Investigator
Victoria Leavitt, PhD
You may be eligible for this study

Place Holder




Who Can I Contact?
For more information, please contact:
Rachael Richards
Email: mscenter_neuro@cumc.columbia.edu
Phone: 212-305-1485