The Effects of 12-months of Denosumab on Bone Density, Quality, and Strength in Prevalent Kidney Transplant Recipients
| Sponsor: |
Amgen |
| Enrolling: |
Male and Female Patients |
| Study Length: |
1 Years |
| Clinic Visits: |
7 |
| IRB Number: |
AAAS3103 |
| U.S. Govt. ID: |
NCT03960554 |
| Contact: |
Maria A. Aponte Farias: 212-305-3273 / maa2308@cumc.columbia.edu |
Kidney transplant patients are at a higher risk for bone fractures compared to the general population. We are doing a clinical trial to examine the effects of 12-months of treatment with denosumab, a monoclonal antibody against RANKL, on bone density and strength as determined by bone imaging and by non-invasive measures of bone activity from blood and questionnaires.
This study is closed
Investigator
Thomas Nickolas, MD, MS
| Have you had a stable kidney transplant that occurred over 1 year ago? |
Yes |
No |
| Do you have a history of cancer? |
Yes |
No |
| Have you had a parathyroidectomy within the past year? |
Yes |
No |
| Are you pregnant or planning on getting pregnant over the course of the study? |
Yes |
No |