Additional Study Information: This 12-week free and confidential outpatient study is recruiting healthy adults who are currently seeking treatment for cocaine use. Participants will engage in twice-weekly clinic visits during which they will have mindfulness-based therapy sessions, meet with a physician, and complete measures with research assistants. Participants will also receive innovative investigational medications twice throughout this trial (Weeks 1 and 5) to help facilitate their engagement in treatment. Upon completion of the study, participants will be referred to appropriate community providers to ensure that they have the necessary means to continue their progress.