RecruitMe Clinical Trial

A Phase 1b, Master Protocol Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of AMG 510 in Subjects With Advanced Solid Tumors With KRAS p.G12C Mutation
Study of AMG510 in Subjects with Advanced Solid Tumors
Enrolling:Male and Female Patients
Minimum Age:18 years old
IRB Number:AAAS7409
Contact: Research Nurse Navigator: 212-342-5162 /
Additional Study Information:

This study is being done to obtain information on the safety and side effects, good or bad, of two new drug combinations; AMG 510 plus trametinib and AMG 510 plus AMG 404. Subjects will participate in one of two research groups. Group A will receive AMG 510 and trametinib. Research Group B will receive AMG 510 and AMG 404.AMG 510 is an anticancer drug that is being developed for tumors with a specific mutation called KRAS p.G12C. AMG 404 is an anticancer drug that works by activating an immune response against the cancer by blocking the activity of a molecule called PD-1. Trametinib is an anticancer drug that interferes with the growth and spread of cancer cells in the body.

Do You Qualify?
Are you at least 18 years old?YesNo
Do you have confirmed locally-advanced or metastatic malignancy?YesNo
Are you able to take oral medications?YesNo
Are you willing to record your daily intake of the study drugs?YesNo
You may be eligible for this study

Place Holder

Who Can I Contact?
For more information, please contact:
Research Nurse Navigator
Phone: 212-342-5162