Inulin for Infections in the Intensive Care Unit (COVID-19)
| Sponsor: |
Department of Defense |
| Enrolling: |
Male and Female Patients |
| IRB Number: |
AAAS2576C |
| U.S. Govt. ID: |
NCT03865706 |
| Contact: |
Elissa Lynch: 212-304-5737 / el2888@cumc.columbia.edu |
Bacterial infections often follow viral illnesses. This research tests whether inulin, a fiber supplement made from chicory root, encourages the growth of good bacteria to prevent infections following COVID-19. This study is being done to test inulin as an investigational new drug (not FDA approved) to prevent bacterial infections after COVID-19. We do not believe that inulin directly treats COVID-19. Instead, the hope is that inulin will prevent a secondary infection, which is often the cause of death in patients with COVID-19. Patients are randomized so that 2 out of 3 patients get the drug but no one knows who will get the drug and who will not. If you choose to participate, you will receive either inulin 32 g/day, inulin 16 g/day, or placebo. A placebo is a liquid or pill that contains no medicine. The inulin or placebo comes as a drink the size of a can of soda that you will drink twice daily. Two thirds of the patients get inulin and 1/3 of the patients get placebo. No one, including you and the medical team, will know whether you are getting inulin or placebo.
This study is closed
Investigator
Daniel Freedberg, MD, MS
| Is the patient 18 years of age or older? |
Yes |
No |
| Has the patient been newly hospitalized in the ICU (within the past 72 hours)? |
Yes |
No |
| Has the patient tested positive for COVID-19? |
Yes |
No |