A Multicenter, Open-Label Phase 1/2 Trial Evaluating the Safety, Tolerability, and Efficacy of MORAb-202, a folate receptor alpha (FR)-targeting antibody-drug conjugate (ADC) in Subjects With Selected Tumor Types
A Study of MORAb-202 in Participants With Selected Tumor Types
Sponsor: Eisai Inc.
Enrolling: Male and Female Patients
IRB Number: AAAS8404
U.S. Govt. ID: NCT04300556
Contact: Research Nurse Navigator: 212-342-5162 / cancerclinicaltrials@cumc.columbia.edu
Additional Study Information: The purpose of the first part of this study, the Dose Escalation part, is to study and identify the highest tolerable safe dose of MORAb-202. Not all patients will get the same dose of the study drug. At the beginning of the study, a small group of three to six patients will receive an infusion with a low dose of the study drug. If this dose does not cause severe side effects, it will be increased for each new group of patients who participate in the study and will continue until the highest tolerable safe dose of the drug is confirmed. This dose will be selected and used as the starting dose for each patient in the Expansion part. The purpose of the Expansion part is to further investigate how the different tumor types being studied respond to the study drug and to gather more information on its safety and effectiveness.
Do You Qualify?
Are you at least 18 years of age? Yes No
Have you been diagnosed with TNBC, EC, NSCLC, primary peritoneal cancer/fallopian tube cancer, or ovarian cancer? Yes No
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For more information, please contact:
Research Nurse Navigator
cancerclinicaltrials@cumc.columbia.edu
212-342-5162