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RecruitMe Clinical Trial

Changes in CSF Biomarkers After Bariatric Surgery
Changes in Brain Biomarkers After Bariatric Surgery or Low-Calorie Diet (ages 18-65)
Enrolling:Male and Female Patients
Age Range:Between 18 and 65 years old
IRB Number:AAAS8430
U.S. Government ID:NCT04350892
Contact: Sarah Borden: 212-305-4006 /
Additional Study Information:

The goal of this project is to understand why bariatric surgery is such an effective treatment for obesity with a focus on brain mechanisms. Cerebrospinal fluid neuropeptides, hormones and protein levels will be measured in subjects before and after bariatric surgery as compared with subjects before and after diet-induced weight loss. Participants in the diet arm will follow a low-calorie liquid diet (Optifast) for approximately 12 weeks. They will have two lumbar punctures (spinal taps) and liquid test meal challenges, as well as weekly nutritionist counseling. These participants will receive $900 for completion of the study. Participants in the surgery arm will begin before their bariatric surgery and be followed for 1 year. They will complete three lumbar punctures and liquid test meal challenges. These subjects will receive $1350 for completion of the study.

Do You Qualify?
Are you between the ages of 18-65?YesNo
Are you obese?YesNo
Within the last 6 months has your weight changed significantly?YesNo
Do you have any medical conditions including heart disease, eating disorders, or high blood pressure?YesNo
Sharon Wardlaw, MD
You may be eligible for this study

Place Holder

Who Can I Contact?
For more information, please contact:
Sarah Borden
Phone: 212-305-4006