RecruitMe Clinical Trial

Phase I study evaluating combination therapy with the receptor tyrosine kinase inhibitor PLX3397 and Sirolimus in patients with unresectable sarcoma and Phase II study in malignant peripheral nerve sheath tumors
A study for patients with malignant peripheral nerve sheath tumors using study drugs PLX3397 and Sirolimus
Sponsor:Plexxikon
Enrolling:Male and Female Patients
Minimum Age:18 years old
IRB Number:AAAO6059
U.S. Government ID:NCT02475213
Contact: Research Nurse Navigator: 212-342-5162 / cancerclinicaltrials@cumc.columbia.edu
Additional Study Information:

The purpose of this study is to determine if treatment with PLX3397 and Sirolimus will be tolerated and result in shrinking of the cancer or stopping the cancer from growing. In the phase I portion, the maximum tolerate dose of the study drug will be determined. In the phase II portion, progression free survival will be assessed at the dose level found in Phase I. Participants will continue to take study drug until they experience an unacceptable side effect or their disease progresses.

Do You Qualify?
Do you have a confirmed diagnosis of malignant peripheral nerve sheath tumors (MPNSTs)YesNo
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Investigator
Gulam Manji, MD, PhD
You may be eligible for this study

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Who Can I Contact?
For more information, please contact:
Research Nurse Navigator
Email: cancerclinicaltrials@cumc.columbia.edu
Phone: 212-342-5162