Sergievsky Center
Yaakov Stern, PhD
Yaakov Stern is the Florence Irving Professor of Neuropsychology in the Departments of Neurology, Psychiatry, and Psychology, and the Taub Institute for the Research on Alzheimer’s Disease and the Aging Brain. Dr. Stern is chief of the Cognitive Neuroscience Division in the Department of Neurology.

Dr. Stern received his BA in Psychology from Touro College in 1975. He received his doctoral training in the Experimental Cognition Program at City University of New York, where he received his PhD in 1983. Dr. Stern began his association with Columbia University Medical Center in 1979, when he began working on his dissertation research on cognition in Parkinson's disease. After receiving his PhD, he was appointed postdoctoral research scientist in 1983, and eventually Professor in 1996.

Dr. Stern’s research focuses on cognition in normal aging and in diseases of aging, particularly Alzheimer’s disease. A strong theme in his research is exploring individual differences in task performance in general and, more specifically, the reason why some individuals show more cognitive deficit than others in the face of brain insult. This has led to the cognitive reserve hypothesis, which provides rationale for intervening to improve cognitive aging. He directs the Reference Ability Neural Network study, a large-scale longitudinal study designed to isolate brain activation and morphological features associated with specific cognitive abilities. He has directed several clinical trials and is currently also involved in several additional, ongoing studies of cognition in normal aging, studies of the heterogeneity of Alzheimer’s disease and epidemiologic studies of aging, Alzheimer’s disease incidence and progression His research approach includes classic neuropsychological and cognitive experimental techniques with a strong focus on functional imaging. He has published over 600 peer-reviewed papers, numerous chapters, and edited a book on cognitive reserve.

Dr. Stern has supervised numerous postdoctoral fellows, many now in faculty positions, and has mentored numerous training awards. He served as associate editor of the Journal of the International Neuropsychological Society, on the editorial board of several journals Neuropsychology and Aging Neuropsychology and Cognition and on the Medical and Scientific Advisory Council, Alzheimer’s Association.

Clinical Studies Managed By This Investigator:
Condition Study Title
Alzheimer's Disease [ CLOSED ] Testing the benefits of the vitamin supplement Benfotiamine in patients with Alzheimer's Disease
Healthy Volunteers [ CLOSED ] Train the Brain Study: Cognitive Training for Older Adults