The purpose of this study is to identify genetic causes of lungdiseases and to develop a research repository so that we can better understand, prevent and treat these conditions. You have been asked to join this study as a healthy control. Even though you do not have lung…
The purpose of this study is to identify genetic causes of lungdiseases and to develop a research repository so that we can better understand, prevent, and treat these conditions. You have been asked to join this study as a healthy control. Even though you do not have …
Are you a current or former smoker? Do you want to know more about your lung health? The FAR-ILD study is designed to detect and study the earliest stages of ILD in at-risk adults, including older smokers. FAR-ILD is a non-interventional study. This means that FAR-ILD is not involved in testing any new interventions or…
The FAR-ILD study is designed to detect and study the earliest stages of ILD in adults with a family history of ILD. FAR-ILD is a non-interventional study. This means that FAR-ILD is not involved in testing any new interventions or therapies. The purpose of FAR-ILD is to gather data on family members of patients with pulmonary fibrosis over a long period of…
The purpose of this study is to determine the efficacy and safety of abituzumab in subjects withsystemic sclerosis-associated interstitial lungdisease (SSc-ILD).Abituzumab is an investigational drug that is being evaluated for the treatment of patients withsystemic sclerosis (SSc)-associated…
This research study is being conducted to study pulmonary hypertension and right heart dysfunction based on clinical, imaging, physiological and pathological characteristics. We hope to develop a new classification system and new methods to diagnose and treat pulmonary hypertension. Diagnostic testing includes (listed subsequently): full medical work-up,…
Systemic sclerosis (SSc) is a systemic connective tissue disease characterized by fibrosis and atrophy, namely of the skin, internal organs, joints, and skeletal muscles. There are numerous manifestations of SSc that affect multiple organ systems. The major pulmonary manifestations of SSc, interstitial …
Patients with hypoplastic left heart syndrome and other single right ventricle lesions who have undergone the Fontan procedure have a high risk of neurodevelopmental disorders that affect quality of life and adulthood employment. This study will leverage the ongoing National Heart, Lung, and Blood Institute (NHLBI)-funded…
The purpose of this study is to determine the effectiveness and safety of a study drug called abituzumab in subjects with systemic sclerosis-associated interstitial lungdisease (SSc-ILD). The study will also look at the following: How the study drug affects other symptoms of SSc-ILD -How safe…