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VGX-3100 Followed by Electroporation with Cellectra for HPV-related High-Grade Squamous Intraepithelial Lesion of Cervix (REVEAL 2)

Condition: Obstetrics & Gynecology
Investigator: June Hou, MD
Status: Closed
The purpose of this study, which involves research, is being done to see how well an investigational new drug and study device combination will work to treat people with pre-cancerous cells on the cervix caused by human papillomavirus (HPV). The treatment combination is testing a drug, called VGX-3100, given by injection and…
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Study of Envafolimab in Patients with Sarcoma or Myxofibrosarcoma

Condition: Cancer / Sarcoma
Investigator: Prabhjot Mundi, MD
Status: Closed
The purpose of this research study is to determine the effectiveness and safety of envafolimab, an experimental drug that is not approved for use, when given alone or in combination with ipilimumab to stimulate your immune system to attack cancer cells. Envafolimab is an experimental (…
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Study of INBRX 109 in Patients with Metastatic or Inoperable Chondrosarcoma

Condition: Cancer / Sarcoma
Investigator: Prabhjot Mundi, MD
Status: Closed
The experimental drug called INBRX 109 has been developed as a treatment for unresectable or metastatic conventional chondrosarcoma. The purpose of this study is to learn about the effects of the study drug, INBRX-109 on you, your immune system, and your cancer. This study is being done to understand if INBRX-109 is effective…
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Study of Paclitaxel With and Without Nivolumab and Nivolumab and Cabozantinib in Taxane Pretreated Subjects with Angiosarcoma

Condition: Cancer / Sarcoma
Investigator: Mark Stein, MD
Status: Closed
The purpose of this study is to: 1. Compare treatment with chemotherapy (paclitaxel) alone to using a combination of nivolumab plus chemotherapy (paclitaxel) treatment in patients with angiosarcoma who have not been treated with paclitaxel chemotherapy alone. 2. Evaluate the effect of nivolumab in combination with cabozantinib on angiosarcoma (cancer) in…
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