Clostridioides difficile (C. difficile) is a bacterium (germ) that can spread from one person to another causing severe diarrhea (watery poop) that at its worst can lead to death. Pfizer has been studying an investigational vaccine to prevent diarrhea caused by C. difficile. To be part of this study you must be 65 years old or older and have one or more of…
This research trial is being conducted to determine the safety and efficacy of HARVONI (an FDA-approved Hepatitis C Virus medication) in HCV (genotype 1, 4, 5, an 6) infected patients who also have advanced heart failure or chronic lungdisease. HARVONI has not been tested in patients with HCV…
The purpose of this study is to determine the safety and effects of a drug, sorafenib in adults diagnosed with hepatopulmonary syndrome (HPS). The study will evaluate how well the drug is tolerated and its effect on the level of oxygen in the blood and the function of the lung vessels. Participants will be randomly assigned to…