The purpose of this study is to identify genetic causes of lungdiseases and to develop a research repository so that we can better understand, prevent and treat these conditions. You have been asked to join this study as a healthy control. Even though you do not have lung…
The purpose of this study is to identify genetic causes of lungdiseases and to develop a research repository so that we can better understand, prevent, and treat these conditions. You have been asked to join this study as a healthy control. Even though you do not have …
Are you a current or former smoker? Do you want to know more about your lung health? The FAR-ILD study is designed to detect and study the earliest stages of ILD in at-risk adults, including older smokers. FAR-ILD is a non-interventional study. This means that FAR-ILD is not involved in testing any new interventions or…
The use of electronic cigarettes, also known as e-cigs or vaping, has increased among former smokers and young adults who have never smoked. Relatively little is known, however, about their health effects (whether they are adverse, have no effect, or are beneficial). The purpose of this research study is to evaluate (1) the association of e-cig use with…
The purpose of this study is to find out if the mitral valve can be safely replaced using a procedure that issimpler than the open-heart procedure being used today and may be safer for patients who are at ahigher risk from conventional open-heart surgery. The device being studied would be implanted without the need for an open-heart procedure and without…
The FAR-ILD study is designed to detect and study the earliest stages of ILD in adults with a family history of ILD. FAR-ILD is a non-interventional study. This means that FAR-ILD is not involved in testing any new interventions or therapies. The purpose of FAR-ILD is to gather data on family members of patients with pulmonary fibrosis over a long period of…
This research study is being conducted to study pulmonary hypertension and right heart dysfunction based on clinical, imaging, physiological and pathological characteristics. We hope to develop a new classification system and new methods to diagnose and treat pulmonary hypertension. Diagnostic testing includes (listed subsequently): full medical work-up,…
The REDUCE LAP-HF I study is being conducted to evaluate the safety and performance of the InterAtrial Shunt Device (IASD) for patients with elevated left atrial pressure who remain symptomatic despite appropriate medical management. Placed by an interventional cardiologist during a standards catheter-based procedure, the IASD system creates a very small…
Patients with hypoplastic left heart syndrome and other single right ventricle lesions who have undergone the Fontan procedure have a high risk of neurodevelopmental disorders that affect quality of life and adulthood employment. This study will leverage the ongoing National Heart, Lung, and Blood Institute (NHLBI)-funded…