Phase 1/2a First-In-Human Study of BMS-986207 Monoclonal Antibody Alone and in Combination with Nivolumab in Advanced Solid Tumors
Sponsor: |
Bristol-Myers Squibb |
Enrolling: |
Male and Female Patients |
IRB Number: |
AAAR0263 |
U.S. Govt. ID: |
NCT02913313 |
Contact: |
Research Nurse Navigator: 212-342-5162 / cancerclinicaltrials@cumc.columbia.edu |
The purpose of the study is to test the safety of an investigational/study drug called BMS-986207 (also known as Anti TIGIT monoclonal antibody) administered alone and in combination with nivolumab. This study will investigate how research subjects/participants with advanced solid tumors tolerate these drugs and identify the highest dose or most suitable dose, of BMS-986207 alone and in combination with nivolumab, in cancer research subjects/participants. This is the first study in which BMS-986207 will be administered to humans. Nivolumab has been administered to and is approved for human use in multiple tumor types. Cancers include Colon cancer, rectal cancer, ovarian cancer, liver cancer, and lung cancer.
This study is closed
Investigator
Alexander Wei, MD
Are you over the age of 18? |
Yes |
No |
Have you been diagnosed with an advanced solid tumor? |
Yes |
No |
Are you able to walk, care for yourself, and do light house or office work? |
Yes |
No |