Additional Study Information: This research study plans to learn more about a device called the Visualase Thermal Therapy System (Visualase system). This device uses a thin laser probe that is inserted into the brain. The laser is turned on, heats up and destroys surrounding soft tissue. Before the surgeon turns on the laser, you will be in a magnetic resonance imaging (MRI) scanner. This lets the surgeon see an image of your brain, the laser probe placement, and how much tissue is being heated up and destroyed while it is happening in real time. Medtronic and participating investigators including the study doctor at Columbia University Medical Center/NY Presbyterian Hospital want to find out if using Visualase is safe and effective for treatment of people with drug resistant mesial temporal lobe epilepsy (MTLE). Drug-resistant MTLE is a condition when antiepileptic drugs (AEDs) do not help control seizures.