A phase I study evaluating the safety and efficacy of SGI-110 followed by combined durvalumab (MEDI4736) plus tremelimumab in subjects with extensive-stage small cell lung cancer (ES-SCLC)
Sponsor: |
Medimmune |
Enrolling: |
Male and Female Patients |
IRB Number: |
AAAQ8257 |
U.S. Govt. ID: |
NCT03085849 |
Contact: |
Catherine Shu, MD: 212-305-3997 / cas2145@columbia.edu |
This study will investigate the safety and effectiveness of the study drug SGI-110 in combination with two immunotherapy drugs named durvalumab and tremelimumab in patients with small cell lung cancer who have progressed on other treatments. SGI-110 is a form of chemotherapy known as a "hypomethylating agent" and may help the immunotherapy work better.
This study is closed
Investigator
Catherine Shu, MD
Are you at least 18 years of age? |
Yes |
No |
Do you have a confirmed diagnosis of small cell lung cancer? |
Yes |
No |