Reducing Cardiovascular Risk in Rheumatoid Arthritis: A Randomized Controlled Clinical Trial Comparing TNF Antagonists With Triple Therapy in Methotrexate Inadequate Responders
Sponsor: |
NIH NIAMS |
Enrolling: |
Male and Female Patients |
Study Length: |
6 Months |
Clinic Visits: |
6 |
IRB Number: |
AAAN5158 |
Contact: |
Rachel Broderick: 212-342-2713 / rb3173@cumc.columbia.edu |
The study aims to compare the effect two different RA treatments on cardiovascular health in patients who are considering a treatment change. The study is recruiting patients who are only taking methotrexate and are switching treatment due to a lack of improvement. The trial will randomize participants to take a TNF inhibitor (Enbrel or Humira) in addition to their methotrexate or to take Triple Therapy (methotrexate + sulfasalazine + hydroxychloroquine sulfate). The study will provide you with all trial medications (excluding methotrexate) for the 6-month duration of the study. Study involvement requires two FDG-PET/CT scans and six follow-up visits over a period of six months.
This study is closed
Investigator
Joan Bathon, MD
Do you have rheumatoid arthritis? |
Yes |
No |
Are you taking methotrexate for rheumatoid arthritis? |
Yes |
No |
Are you interested in learning more about the impact of rheumatoid arthritis medications on cardiovascular health? |
Yes |
No |