Phase I/II Trial of Ruxolitinib in Combination with Trastuzumab in Metastatic HER2 Positive Breast Cancer
Sponsor: |
Incyte Corporation |
Enrolling: |
Male and Female Patients |
IRB Number: |
AAAM1906 |
U.S. Govt. ID: |
NCT02066532 |
Contact: |
Kevin Kalinsky, MD, MS: 212-305-1945 / kk2693@cumc.columbia.edu |
The purpose of this study is to determine whether the combination of study drugs Ruxolitinib plusTrastuzumab is safe and effective in stopping breast tumor growth in patients with HER2 positivemetastatic breast tumors who have already received Trastuzumab. Trastuzumab (Herceptin) is an FDA-approved treatment for HER2 positive breast cancer.
This study is closed
Investigator
Kevin Kalinsky, MD, MS
Do you have locally recurrent or metastatic breast cancer? |
Yes |
No |
Have you had prior therapy with pertuzumab and ado-trastuzumab? |
Yes |
No |
Are you able to swallow, retain, and absorb medication by mouth? |
Yes |
No |