HCT Matched Related Hematopoietic Stem Cell Tranplantation for Children with Less Severe Sickle Cell Disease: a Sickle Transplant Alliance for Research (STAR) Trial
Sponsor: |
STAR |
Enrolling: |
Male and Female Patients |
Study Length: |
2 Years |
IRB Number: |
AAAS6455 |
Contact: |
Brian Volonte: 212-304-7806 / bv2272@cumc.columbia.edu |
The primary objectives of this study are to measure the safety and effectiveness of bone marrow transplant (BMT) using specific chemotherapy in children with less severe SCD and to understand the long term effects of bone marrow transplant in children with SCD, by evaluating ovarian reserve, sickle cell related brain problems, sickle cell related kidney problems and health related quality of life.
This study is closed
Investigator
Monica Bhatia, MD
Hgb SS or HbS Beta Thalassemia |
Yes |
No |
HLA identical donor |
Yes |
No |
Previous stroke or abnormal TCD |
Yes |
No |
Frequent (3/year for preceeding 2 years) VOCs or Acute Chest Events |
Yes |
No |
Normal organ function |
Yes |
No |