An Open-Label, Multi-Drug, Biomarker-Directed, Multi-Center Phase II Umbrella Study in Patients with Non-Small Cell Lung Cancer, who Progressed on an anti-PD-1/PD-L1 Containing Therapy (HUDSON)
Sponsor: |
AstraZeneca |
Enrolling: |
Male and Female Patients |
IRB Number: |
AAAR6575 |
U.S. Govt. ID: |
NCT03334617 |
Contact: |
Research Nurse Navigator: 212-342-5162 / cancerclinicaltrials@cumc.columbia.edu |
This is an open-label, Phase II study in patients with metastatic non-small cell lung cancer (NSCLC) whose cancer has gotten worse on an anti-programmed cell death-1/anti-programmed cell death ligand 1 (anti-PD-1/PD-L1) containing therapy. This study consists of a number of treatment cohorts to test the efficacy, safety, and tolerability of multiple treatment arms. There is currently no established therapy for patients who have received immune checkpoint inhibitors and platinum-doublet therapies, and new treatments are urgently needed.
This study is closed
Investigator
Catherine Shu, MD
Are you 18 years or older? |
Yes |
No |
Have you been diagnosed with metastatic or recurrent non-small cell lung cancer? |
Yes |
No |
Has your disease worsened following treatment with chemotherapy and an anti-PD-1/PD-L1 therapy (ex. Opdivo or Keytruda)? |
Yes |
No |