Prospective Evaluation of Carvedilol in Prevention of Cardiac Toxicity in Patients with Metastatic HER-2+ Breast Cancer, Phase III
		
	
		
			
				| Sponsor: | 
				NIH | 
			
			
			
				| Enrolling: | 
									Male and Female Patients | 
							
						
			
			
                            
                    | IRB Number: | 
                    AAAR6417 | 
                
            
					
			
				| Contact:  | 
				Research Nurse Navigator: 212-342-5162 / cancerclinicaltrials@cumc.columbia.edu | 
			
		
	
		To assess whether prophylactic beta blocker therapy with carvedilol compared with no intervention reduces the risk of subsequent cardiac dysfunction in patients with metastatic breast cancer receiving trastuzumab-based HER-2 targeted therapy.
	
			This study is closed
	
	   	
		Investigator
		
		Katherine Crew, MD
		
					   
	
		
		
		
			
				
					| Have you been diagnosed with metastatic breast cancer? | 
					Yes | 
					No | 
				
				
									
						| Haveyou received HER-2 targeted therapy? | 
						Yes | 
						No |