RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL-GROUP, MULTICENTER, PHASE II STUDY TO EVALUATE THE EFFICACY AND SAFETY OF MTAU9937A IN PATIENTS WITH PRODROMAL-TO-MILD OR MODERATE ALZHEIMER'S DISEASE
Sponsor: |
Genentech, Inc. |
Enrolling: |
Male and Female Patients |
IRB Number: |
AAAR6047 |
U.S. Govt. ID: |
NCT03289143 |
Contact: |
Katrina Cuasay: 212-305-2371 / kc2305@cumc.columbia.edu |
This is a Phase II, randomized, double-blind, placebo-controlled, parallel-group study that will evaluate the efficacy, safety and tolerability, pharmacokinetics, and pharmacodynamics of the study drug (an antibody to the tau protein called MTAU9937A) in patients with prodromal or mild Alzheimer's disease. The study consists of a screening period, a double-blind treatment period, an optional open-label extension (OLE) period, and a safety follow-up period.
This study is closed
Investigator
Lawrence Honig, MD, PhD
Do you meet the clinical criteria for probably AD dementia or prodromal AD? |
Yes |
No |
Do you have a history of schizophrenia, schizoaffective disorder, major depression, or bipolar disorder? |
Yes |
No |
Do you weigh between 40 and 120 kg, inclusive (88-264 pounds)? |
Yes |
No |