Phase 1, window of opportunity study of parasympathetic stimulation with bethanechol in localized pancreatic adenocarcinoma prior to surgery
Study of Stimulation with Bethanechol in Pancreatic Adenocarcinoma Prior to Surgery
Sponsor: American Association for Cancer Research
Enrolling: Male and Female Patients
IRB Number: AAAR6735
U.S. Govt. ID: NCT03572283
Contact: Research Nurse Navigator: 212-342-5162 / cancerclinicaltrials@cumc.columbia.edu
Additional Study Information: The purpose of this study is to determine whether the drug, bethanechol, could potentially be used in combination with surgery to decrease the chance of the cancer coming back after it is removed. Bethanechol is a medication that regulates the parasympathetic nervous system and is often used to manage the side effects of chemotherapy drugs and to manage urinary retention. Studies of pancreatic cancer in animal models have shown that treatment with bethanechol can inhibit cancer growth and spread. People with pancreatic cancer localized to a small area usually undergo surgery to remove the tumor.
Investigator
Susan Bates, MD
Do You Qualify?
Are you 18 years or older? Yes No
Do you have a confirmed diagnosis of pancreatic ductal adenocarcinoma or are you willing to undergo a biopsy prior to therapy? Yes No
Do you have a predicted life expectancy of greater than 3 months? Yes No
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For more information, please contact:
Research Nurse Navigator
cancerclinicaltrials@cumc.columbia.edu
212-342-5162