A Phase 1/2 Study of REGN4018 (A MUC16xCD3 Bispecific Antibody) Administered Alone or in Combination with Cemiplimab in Patients with Recurrent Ovarian Cancer
Sponsor: |
Regeneron Pharmaceuticals, Inc. |
Enrolling: |
Female Patients Only |
IRB Number: |
AAAR8226 |
U.S. Govt. ID: |
NCT03564340 |
Contact: |
Research Nurse Navigator: 212-342-5162 / cancerclinicaltrials@cumc.columbia.edu |
The main purpose of this study is to: Learn about the safety of REGN4018 and to find out what dose of REGN4018 can be given alone or in combination with cemiplimab to research subjects with ovarian cancer without too many side effects. The study will also look at the levels of REGN4018 and/or cemiplimab in the body and measure how well your body can remove the study drug(s). This is called pharmacokinetics. The study will also look at any signs that REGN4018 alone or with cemiplimab can treat cancer.
Investigator
June Hou, MD
Are you a woman who is 18 years of age or older? |
Yes |
No |
Do you have ovarian cancer? |
Yes |
No |
Are you willing and able to comply with clinic visits and study-related procedures, including undergoing study biopsies? |
Yes |
No |