A Phase 1/2 Study of CPI-0610, a Small Molecule Inhibitor of BET Proteins: Phase 1 (Dose Escalation of CPI-0610 in Patients with Hematological Malignancies) and Phase 2 (Dose Expansion of CPI-0610 with and without Ruxolitinib in Patients with Myelofibrosis)
Sponsor: |
Constellation Pharmaceuticals |
Enrolling: |
Male and Female Patients |
IRB Number: |
AAAR8502 |
U.S. Govt. ID: |
NCT02158858 |
Contact: |
Research Nurse Navigator: 212-342-5162 / cancerclinicaltrials@cumc.columbia.edu |
We are doing this study to find out if an investigational drug called CPI-0610 can help with myelofibrosis. An investigational drug is a drug that is not approved for sale in the United States by the Food and Drug Administration (FDA). This study has two groups (arms) one group of patients will be treated with CPI-0610 alone (monotherapy arm) and the other group of patients will be treated with CPI-0610 in combination with ruxolitinib (combination arm).
This study is closed
Investigator
Mark Heaney, MD, PhD
Are you 18 years or older? |
Yes |
No |
Do you have myelofibrosis (MF)? |
Yes |
No |