Randomized Trial of Standard Chemotherapy Alone or Combined with Atezolizumab as Adjuvant Therapy for Patients with Stage III Colon Cancer and Deficient DNA Mismatch Repair
Sponsor: |
NIH |
Enrolling: |
Male and Female Patients |
IRB Number: |
AAAR9052 |
U.S. Govt. ID: |
NCT02912559 |
Contact: |
Research Nurse Navigator: 212-342-5162 / cancerclinicaltrials@cumc.columbia.edu |
This study evaluates whether the addition of immune therapy to usual FOLFOX chemotherapy in patients with deficient DNA mismatch repair stage III colon cancer can improve your outcome compared to FOLFOX alone. The immune therapy drug, atezolizumab, may allow your body's immune system to more effectively kill cancer cells in your body. One of the purposes of this study is to determine if giving atezolizumab and the chemotherapy FOLFOX decreases the risk of colon cancer recurrence to a greater degree than does FOLFOX chemotherapy alone.
This study is closed
Investigator
Yoanna Pumpalova, MD
Are you 18 years of age or older? |
Yes |
No |
Do you have stage III colon adenocarcinoma? |
Yes |
No |
Have you had complete resection of your tumor? |
Yes |
No |
Have you had no prior medical therapies? |
Yes |
No |