A Phase Ib, multicenter, open-label dose escalation and expansion platform study of select immunotherapy combinations in adult patients with triple negative breast cancer
Sponsor: |
Novartis |
Enrolling: |
Male and Female Patients |
IRB Number: |
AAAS1826 |
U.S. Govt. ID: |
NCT03742349 |
Contact: |
Research Nurse Navigator: 212-342-5162 / cancerclinicaltrials@cumc.columbia.edu |
The purpose of this study is to identify the doses of spartalizumab (PDR001) with LAG525 in combination with either NIR178, capmatinib (INC280), MCS110 or canakinumab (ACZ885) that can be given safely. The study will also test how well spartalizumab (PDR001) with LAG525 in combination with either NIR178, capmatinib (INC280), MCS110 or canakinumab (ACZ885) might work in treating patients with TNBC.
This study is closed
Investigator
Meghna Trivedi, MD
Are you 18 years of age or older? |
Yes |
No |
Have you been diagnosed with breast cancer? |
Yes |
No |
Have you had no more than 2 prior treatments for breast cancer? |
Yes |
No |
Are you willing to possibly undergo additional biopsies? |
Yes |
No |