Uncovering Neural Mechanisms of Chronic Pain in Post-Treatment Lyme Syndrome (Lyme Disease)
A Brain Imaging Study of Chronic Pain in Post-Treatment Lyme Disease
Sponsor: Columbia Lyme & Tick-borne Diseases Research Center
Enrolling: Male and Female Patients
Clinic Visits: 2
IRB Number: 7756
Contact: Lyme Center: 646-774-7503 / lymecenter@cumc.columbia.edu
Additional Study Information: Why do some individuals continue to experience chronic symptoms of Lyme Disease, such as pain, long after receiving treatment? Through the use of brain imaging (functional MRI) and specific biomarker testing, we hope to gain a better understanding as to why patients develop this persistent, debilitating pain. Based on prior research, we explore whether Lyme disease may change the pattern of an brain activation, making the person more sensitive to pain than a healthy person. If we identify the hyper-activated brain networks in patients with chronic Lyme symptoms, then that information can inform the design of better diagnostic tests as well as new treatment methods that target symptom reduction. We are inviting patients who continue experiencing chronic pain after being treated for Lyme Disease to participate in our study. Study participation will involve a) evaluation: interview and blood test (about 1.5-2 hours; the interview and blood tests can be done remotely or in-person at our institute) and b) a visit to CUIMC for brain imaging, neurocognitive and other tests of sensory sensitivity (total visit time about 5-6 hours, including a break for lunch). If you are interested in participating, please also email us at lymecenter@cumc.columbia.edu with the email subject "fMRI study" and indicate your age and gender in the email.
This study is closed
Alla Landa, PhD
Do You Qualify?
Have you been diagnosed and treated for Lyme Disease? Yes No
Are you between the ages of 18 and 55 years old? Yes No
Are you right-handed? Yes No
Do you have any non-removable metal in your body? (ie. pacemaker, surgical implant, braces, etc.) Yes No
Do you have have any blue (metallic ink) tattoos? Yes No
You may be eligible for this study

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For more information, please contact:
Lyme Center