A Phase 1, Open-Label, Dose-Escalation and Cohort Expansion First-in-Human Study of the Safety, Tolerability, Activity and Pharmacokinetics of REGN3767 (anti-LAG-3mAb) Administered Alone or in Combination with REGN2810 (anti-PD-1 mAb) in Patients with Advanced Malignancies
Sponsor: |
Regeneron Pharmaceuticals, Inc. |
Enrolling: |
Male and Female Patients |
IRB Number: |
AAAS1963 |
U.S. Govt. ID: |
NCT03005782 |
Contact: |
Research Nurse Navigator: 212-342-5162 / cancerclinicaltrials@cumc.columbia.edu |
This study is being done to find a safe dose level of REGN3767 alone or in combination with REGN2810. Other purposes of this study are to measure the levels of REGN3767 alone or in combination with REGN2810 in your blood and to collect any evidence of tumor shrinkage when given alone or in combination with REGN2810. These drugs are not yet approved.
This study is closed
Investigator
Alexander Wei, MD
Do you have breast, lung, melanoma, or thyroid cancer? |
Yes |
No |
Does your cancer continue to grow even after receiving treatment, or is there no available therapy for your cancer? |
Yes |
No |
Are you 18 years of age or older? |
Yes |
No |