Additional Study Information: The purpose of this study is to study two experimental drugs called canakinumab and spartalizumab produced by Novartis to see if: It is safe and feasible to give canakinumab and spartalizumab prior to radical nephrectomy? Canakinumab and spartalizumab can kill cancer cells and bring immune cells into the kidney cancer when given to human subjects prior to radical nephrectomy? You are being asked to participate in this study because you have localized kidney cancer and you are planned to have a radical nephrectomy. People who usually have this do not receive any additional treatments prior to surgery despite significant risk that the cancer will recur. This is a pilot study to evaluate the safety and feasibility of a new treatment designed to target your body's immune cells against your kidney cancer prior to surgery. Approximately 14 individuals will be asked to participate in this study.