A Phase 1b/2 Open Label, Dose Escalation and Expansion Study of the Glutaminase Inhibitor CB-839 in Combination with the PARP inhibitor Talazoparib in Patients with Advanced or Metastatic Solid Tumors
Sponsor: |
Calithera Biosciences, Inc |
Enrolling: |
Male and Female Patients |
IRB Number: |
AAAS2587 |
U.S. Govt. ID: |
NCT03875313 |
Contact: |
Research Nurse Navigator: 212-342-5162 / cancerclinicaltrials@cumc.columbia.edu |
The purpose of this study is to determine a safe and tolerable dose of CB-839 (an investigational drug), given together with talazoparib , and if it has an effect on your type of cancer. Subjects with advanced or metastatic (spread of cancer from the primary site to other places in the body) solid tumors will be included in this study.
This study is closed
Investigator
Kevin Kalinsky, MD, MS
Are you 18 years of age or older? |
Yes |
No |
Have you been diagnosed with advanced or metastatic solid tumors? |
Yes |
No |