A Phase 2, Multicohort, Open-label, Multicenter Study to Evaluate the Efficacy and Safety of bb2121 in Subjects With Relapsed and Refractory Multiple Myeloma and in Subjects With Clinical High-Risk Multiple Myeloma (KarMMa-2)
Sponsor: |
Celgene Corporation |
Enrolling: |
Male and Female Patients |
IRB Number: |
AAAR9953 |
U.S. Govt. ID: |
NCT03601078 |
Contact: |
Research Nurse Navigator: 212-342-5162 / cancerclinicaltrials@cumc.columbia.edu |
The purpose of this study is to determine if the investigational therapy called bb2121 is effective in treating multiple myeloma. bb2121 is a type of therapy known as chimeric antigen receptor (CAR) T-cell therapy. T cells are a kind of white blood cell which form part of your body's immune system. Your T cells will be separated from the rest of the immune cells and then modified to make the bb2121 T cells. The bb2121 T cells manufactured for you will be shipped to the study site when you are ready for the treatment and infused back into your blood.
Investigator
Ran Reshef, MD
Are you 18 years of age or older? |
Yes |
No |
Were you diagnosed with multiple myeloma? |
Yes |
No |
Did your cancer return after your most recent treatment regimen, or has your cancer not responded to your most recent treatment? |
Yes |
No |