A Phase 1b Study of ASP1951, a GITR Agonistic Antibody, as a Single Agent and in Combination with Pembrolizumab in Subjects with Advanced Solid Tumors
Sponsor: |
Astellas Pharma Global Development, Inc. |
Enrolling: |
Male and Female Patients |
IRB Number: |
AAAS2018 |
U.S. Govt. ID: |
NCT03799003 |
Contact: |
Research Nurse Navigator: 212-342-5162 / cancerclinicaltrials@cumc.columbia.edu |
The main purpose of the study is to determine at what dose the study drug (ASP1951) is safe and tolerated and how it is processed in the blood of subjects with tumors that cannot be removed (unresectable) or has spread (metastasized) to a different part of the body. When the safe dose is identified, it will be used to evaluate if the study drug treatment causes tumors to shrink in subjects. During this period, the subjects will be continuously assessed to determine if the study drug is safe and tolerable.
This study is closed
Investigator
Brian Henick, MD
Do you have tumor(s) that cannot be removed (unresectable) or has spread (metastasized) to a different part of the body? |
Yes |
No |
Are you willing to possibly undergo biopsies during the study? |
Yes |
No |
Are you 18 years of age or older? |
Yes |
No |