YO40482: A PHASE Ib STUDY OF COBIMETINIB ADMINISTERED IN COMBINATION WITH NIRAPARIB, WITH OR WITHOUT ATEZOLIZUMAB, TO PATIENTS WITH ADVANCED PLATINUM-SENSITIVE OVARIAN CANCER
Sponsor: |
F. Hoffmann-La Roche Ltd |
Enrolling: |
Female Patients Only |
IRB Number: |
AAAS0353 |
U.S. Govt. ID: |
NCT03695380 |
Contact: |
Reena Vattakalam: 212-342-6895 / rmv2110@cumc.columbia.edu |
The purpose of this study is to find out what effects, good or bad, cobimetinib and niraparib, given with or without atezolizumab, have on you and your cancer. In this study, you will receive either cobimetinib plus niraparib or cobimetinib plus niraparib plus atezolizumab. In addition, if you are assigned to receive cobimetinib and niraparib and your cancer progresses, you could receive atezolizumab along with cobimetinib and niraparib if your doctor believes that you may benefit from this treatment.
This study is closed
Investigator
Jason Wright, MD
Have you been diagnosed with endometrioid epithelial ovarian, fallopian tube, or primary peritoneal cancer? |
Yes |
No |
Have you received 1-2 prior platinum-containing treatment regimens? |
Yes |
No |