A Multicenter, Open-Label, Randomized Phase III Study to Evaluate the Efficacy and Safety of the Combination of Belantamab Mafodotin, Bortezomib, and Dexamethasone (B-Vd) Compared with the Combination of Daratumumab, Bortezomib and Dexamethasone (D-Vd) in Participants with Relapsed/Refractory Multiple Myeloma
Sponsor: |
GlaxoSmithKline |
Enrolling: |
Male and Female Patients |
IRB Number: |
AAAT0104 |
U.S. Govt. ID: |
NCT04246047 |
Contact: |
Research Nurse Navigator: 212-342-5162 / cancerclinicaltrials@cumc.columbia.edu |
Belantamab Mafodotin is a new therapy for patients with Multiple Myeloma. The drug works by combining chemotherapy and immunotherapy approach to treat Multiple Myeloma. The drug is a combination of an antibody against a target on plasma cells called BCMA and a chemotherapeutic agent called MMAF. The drug has shown activity in patients with late relapses of Multiple Myeloma. Because of its unique mechanism of action and activity, this trial will test the drug in patients with early relapse to evaluate if the drug in combination with Bortezomib and Dexamethasone will have better outcomes than the current standard of care.
This study is closed
Investigator
Divaya Bhutani, MD
Are you 18 years of age or older? |
Yes |
No |
Have you received previous treatment for multiple myeloma? |
Yes |
No |
Did you have disease progression during or after your treatment? |
Yes |
No |