NAUTIKA1: A MULTICENTER, PHASE II, NEOADJUVANT AND ADJUVANT STUDYOF MULTIPLE THERAPIES IN BIOMARKER-SELECTED PATIENTS WITH RESECTABLE STAGES IBIII NON-SMALL CELL LUNG CANCER
Sponsor: |
Genentech, Inc. |
Enrolling: |
Male and Female Patients |
IRB Number: |
AAAS8662 |
U.S. Govt. ID: |
NCT04302025 |
Contact: |
Research Nurse Navigator: 212-342-5162 / cancerclinicaltrials@cumc.columbia.edu |
The purpose of this study is to evaluate the safety and efficacy of different experimental targeted cancer therapies (not approved by the FDA for treatment of your type of cancer) in patients who have stage IA2, IB, II, IIA, or selected IIIB non-small cell lung cancer tumors that are untreated and able to be removed by surgery. The treatments that will be investigated are the study drugs alectinib, entrectinib, and vemurafenib plus cobimetinib. Based off of individual molecular abnormalities, each participant will be assigned to either the alectinib, entrectinib, or vemurafenib plus cobimetinib study group.
Investigator
Catherine Shu, MD
Are you at least 18 years of age? |
Yes |
No |
Have you been diagnosed with non-small cell lung cancer? |
Yes |
No |
Do you have tumors that are able to be removed by surgery? |
Yes |
No |