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Functional Brain Mechanisms Underlying the Anti-suicidal Effects of Buprenorphine in Opioid Use Disorder
Functional Brain Mechanisms Underlying the Anti-Suicidal Effects of Buprenorphine in Opioid Use Disorder
| Sponsor: | Columbia University |
| Enrolling: | Male and Female Patients |
| Study Length: | 3 Weeks |
| IRB Number: | 7855 |
| U.S. Govt. ID: | NCT04234516 |
| Contact: | Dr. Mina Rizk: 646-774-7518 / mina.rizk@nyspi.columbia.edu |
Additional Study Information:
This research study uses MRI scans to compare the effect of two medications on suicidal thoughts and brain activity in people who have opioid use disorder. We hope to develop a better understanding of how well these two medications help depression and suicidal thoughts. You may qualify if you have opioid use disorder and suicidal thoughts. Participation involves a detailed diagnostic set of interviews, brain imaging scans (MRI), and neuropsychological tasks. Eligible individuals will be hospitalized and receive free medication-based treatments for the duration of the study (3 weeks).
This study is closed
Do You Qualify?
| Are you between the ages 18-65 years? | Yes | No |
| Do you currently have opioid use disorder? | Yes | No |
| Are you seeking treatment for opioid use disorder and willing to be stabilized on buprenorphine when the study is over? | Yes | No |
| Do you have active suicidal thoughts? | Yes | No |
| Are you currently pregnant, breastfeeding, or trying to become pregnant? | Yes | No |