Dopaminergic Dysfunction in Late-Life Depression (The D3 Study)
Research Study for Older Adults Feeling Slowed Down and Depressed
Sponsor: National Institute of Mental Health
Enrolling: Male and Female Patients
IRB Number: 7976
U.S. Govt. ID: NCT04493320
Contact: Manya Balachander: 646-774-8677 /
Additional Study Information: The purpose of this research study is to better understand the brain's dopamine system among older adults with depression. The dopamine system plays important roles in thinking, movement, motivation, and pleasurable or rewarding activities. In addition to performing brain scans and several different tests of your thinking and movement, we use a medication called carbidopa/levodopa (Sinemet) to investigate how the brain's dopamine levels influence behavior. We are using carbidopa/levodopa "off-label" in this study, which means that it is not approved by the Food and Drug Administration for the treatment of depression.
This study is closed
Do You Qualify?
Are currently depressed? Yes No
Are you 60 years of age or older? Yes No
Do you feel physically and/or mentally slowed down? Yes No
You may be eligible for this study

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For more information, please contact:
Manya Balachander