A Phase 1b/3 Double-blind, Randomized, Active-controlled, 3-stage, Biomarker Adaptive Study of Tazemetostat or Placebo in Combination With Lenalidomide Plus Rituximab in Subjects With Relapsed/Refractory Follicular Lymphoma
Sponsor: |
Epizyme, Inc. |
Enrolling: |
Male and Female Patients |
IRB Number: |
AAAT0518 |
U.S. Govt. ID: |
NCT04224493 |
Contact: |
Research Nurse Navigator: 212-342-5162 / cancerclinicaltrials@cumc.columbia.edu |
The purpose of the study is to evaluate the safety and tolerability of tazemetostat in combination with lenalidomide + rituximab in patients with follicular lymphoma that has returned or has not responded to treatment (relapsed/refractory). The study will also try to select a recommended phase 3 dose of tazemetostat for further evaluation.
Investigator
Jennifer Amengual, MD
Are you 18 years of age or older? |
Yes |
No |
Do you have follicular lymphoma? |
Yes |
No |
Has your disease relapsed or progressed during/after treatment? |
Yes |
No |
Are you able to take oral medication? |
Yes |
No |