Additional Study Information: The purpose of this study is to test the study drug ruxolitinib to see how well the drug works on your disease. This study will also explore potential biomarkers for ruxolitinib by examining your blood and tissue for genes and proteins that can help identify and/or predict whether therapy would benefit someone or not. Your tissue samples contain biomarkers such as proteins. Due to your illness, these proteins can be abnormal. For example, there can be too many proteins, or the proteins may be overactive. These abnormal proteins may promote cancer growth. Testing on your tumor samples allows us to fully study biomarkers and answer questions from health authorities about the way the drugs work in this research project.