Additional Study Information: The purpose of this study is to evaluate how safe and effective the NanoKnife System is at treating Stage 3 pancreatic adenocarcinoma. This is registry study and therefore, the NanoKnife System is not being used for study purposes. The safety and efficacy of this system will be evaluated by comparing survival rates, pain ratings, and number of adverse events between a group of subjects who receive treatment with the NanoKnife System, and a group of subjects who receive standard of care treatment for their disease.