A Phase I, Open-label, Dose Escalation Study of Oral LGK974 in Patients With Malignancies Dependent on Wnt Ligands
Sponsor: |
Novartis Pharmaceuticals |
Enrolling: |
Male and Female Patients |
IRB Number: |
AAAT0131 |
U.S. Govt. ID: |
NCT01351103 |
Contact: |
Research Nurse Navigator: 212-342-5162 / cancerclinicaltrials@cumc.columbia.edu |
This primary purpose of this study is to find the recommended dose of LGK974 and PDR001 that can be safely given to adult patients who have advanced metastatic pancreatic cancer, or triple negative breast (TNB) cancer, or melanoma, lung squamous cell cancer, esophageal squamous cell cancer, cervical squamous cell cancer, or head and neck squamous cell cancer (HNSCC).
This study is closed
Investigator
Richard Carvajal, MD
Are you at least 18 years old? |
Yes |
No |
Do you have a diagnosis of advanced or metastatic cancer that has progressed despite standard therapy? |
Yes |
No |