Harnessing Hormonal Variation to Probe Neural Mechanisms and Optimize CBT Outcomes for OCD
How Hormones and Exposure and Response Prevention (EX/RP) Affect the Brain of People with OCD
Sponsor: National Institute of Mental Health NIMH
Enrolling: Male and Female Patients
IRB Number: 8227
U.S. Govt. ID: NCT05359562
Contact: Marite Horton: 646-774-8062 / marite.horton@nyspi.columbia.edu
Additional Study Information: Studies show that hormones affect the brain's fear extinction network, which is relevant for therapy involving exposure and response prevention (EX/RP), a first-line treatment for obsessive compulsive disorder (OCD). This study will examine the effect of delivering EX/RP to women during different phases in their menstrual cycle to determine the effects of hormones on the fear extinction network and on their OCD symptoms. Men will also be recruited for this study to further explore biological sex differences.
This study is closed
Helen Simpson, MD, PhD
Do You Qualify?
Are you currently suffering from obsessive-compulsive disorder (OCD)? Yes No
Are you currently taking psychiatric medications? Yes No
Do you have MRI-unsafe metal in your body? Yes No
You may be eligible for this study

Place Holder

For more information, please contact:
Marite Horton