Harnessing Hormonal Variation to Probe Neural Mechanisms and Optimize CBT Outcomes for OCD
Sponsor: |
National Institute of Mental Health NIMH |
Enrolling: |
Male and Female Patients |
IRB Number: |
8227 |
U.S. Govt. ID: |
NCT05359562 |
Contact: |
Marite Horton: 646-774-8062 / marite.horton@nyspi.columbia.edu |
Studies show that hormones affect the brain's fear extinction network, which is relevant for therapy involving exposure and response prevention (EX/RP), a first-line treatment for obsessive compulsive disorder (OCD). This study will examine the effect of delivering EX/RP to women during different phases in their menstrual cycle to determine the effects of hormones on the fear extinction network and on their OCD symptoms. Men will also be recruited for this study to further explore biological sex differences.
This study is closed
Investigator
Helen Simpson, MD, PhD
Are you currently suffering from obsessive-compulsive disorder (OCD)? |
Yes |
No |
Are you currently taking psychiatric medications? |
Yes |
No |
Do you have MRI-unsafe metal in your body? |
Yes |
No |