Additional Study Information: In this research study, we want to find out how well patients that receive a kidney from an HIV-positive (HIV+) donor do over 10 years compared to patients who receive a kidney from an HIV-negative (HIV-) donor. This research study is for adults who are HIV+ and are being evaluated for or are waitlisted to receive a kidney transplant. It is also available for adults who are HIV+ and previously received a kidney-only transplant under a HOPE Act protocol. To take part in this study you must be willing to accept a kidney from an HIV+ or HIV- donor. If you decide not to join this study, you will still be eligible to receive kidney offers from HIV- donors, but you will not be able to receive kidney offers from HIV+ donors. If you join this study pre-transplant, you will have blood drawn around the time of transplant and a biopsy will be taken from the donor kidney before the transplant. For all study subjects, you will have research blood collected at scheduled study visits. We will collect data from your medical records for at least one year post-transplant. We will continue to collect data for up to 10 years post-transplant, depending on when the study ends.