A Three-part, Phase I/II Dose-Escalation Study to Define the Safety, Tolerability, and Optimal Dose of Candidate GBM vaccine VBI-1901 with Subsequent Extension of Optimal Dose in Recurrent GBM subjects.
Sponsor: |
VBI Vaccines, Inc. |
Enrolling: |
Male and Female Patients |
IRB Number: |
AAAR5300 |
U.S. Govt. ID: |
NCT03382977 |
Contact: |
Research Nurse Navigator: 212-342-5162 / cancerclinicaltrials@cumc.columbia.edu |
The purpose of this study is to test the safety of a new vaccine, VBI-1901, and to know more about its ability to boost the response of the immune system against Cytomegalovirus. The reason for testing this vaccine in people with a brain tumor is that it might one day be used to boost the ability of the immune system to fight a certain type of brain tumor. This type of treatment for brain tumors is called immunotherapy.
Investigator
Andrew Lassman, MD
Are you between the ages of 18-70? |
Yes |
No |
Have you been diagnosed with a glioblastoma (type of brain cancer)? |
Yes |
No |
Has your tumor come back or progressed after an initial treatment? |
Yes |
No |
Have you recovered from surgery? |
Yes |
No |