A Phase I/II, multi-center, open-label study of DYP688 in patients with metastatic uveal melanoma (MUM) and other GNAQ/11 mutant melanomas
Sponsor: |
Novartis |
Enrolling: |
Male and Female Patients |
IRB Number: |
AAAU2610 |
U.S. Govt. ID: |
NCT05415072 |
Contact: |
Research Nurse Navigator: 212-342-5162 / cancerclinicaltrials@cumc.columbia.edu |
The purpose of this study is to identify the safest and most tolerable dose of the study drug, DYP688 that can be given to patients. Also to evaluate how well DYP688 might work in treating certain types of cancer including metastatic uveal melanoma and other melanomas with GNAQ/11 mutations (or genetic changes to the gene GNAQ/11). Metastatic means the disease has spread from an initial or primary site to different areas of the body. DYP688 is a study treatment that has not been approved by the FDA. This study is the first time the study drug is being tested in humans.
Investigator
Alexander Wei, MD
Are you at least 18 years old? |
Yes |
No |
Have you been diagnosed with melanoma? |
Yes |
No |