A Multimodal Imaging Study of Dopamine in Early Psychosis
Imaging Study for People with Unusual Thoughts and Experiences
Sponsor: NIMH
Enrolling: Male and Female Patients
Study Length: 2 Years
Clinic Visits: 12
IRB Number: 8361
Contact: COPE Clinic: 646-774-5232 / cope@nyspi.columbia.edu
Additional Study Information: Are you between the ages of 18-30? Have you ever experienced unusual thoughts, experiences or feelings? Or, do you have a first-degree relative (e.g., sibling, parent, child) with schizophrenia, psychosis, or a psychotic disorder? If so, you may be eligible for a brain imaging research study that aims to understand the relationship between a chemical called dopamine and these types of thoughts. Study requirements: Physical exam, blood draw, urine sample at the Columbia University Irving Medical Center(CUIMC)/New York State Psychiatric Institute (NYSPI) 3-4 hours of interviews, one MRI scan of the brain (up to 1 hour), two PET (Positron Emission Tomography), scans on the same day, and one dose of methylphenidate. Methylphenidate is what is called a stimulant medication that can make people feel more awake, alert, and attentive. It is given for conditions such as attention deficit hyperactivity disorder and narcolepsy. As a participant, you will receive: Up to $1300, as well as reimbursement for local transportation. For further information about the study and your eligibility, please contact the Center of Prevention and Evaluation (COPE) Clinic at the New York State Psychiatric Institute at 646-774-5232.
This study is closed
Ragy Girgis, MD
Do You Qualify?
Are you between the ages of 18 and 30? Yes No
Do you live in the New York metropolitan area? Yes No
Have you ever had unusual thoughts, experiences or feelings, or do you have a family member with schizophrenia or psychosis? Yes No
You may be eligible for this study

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For more information, please contact:
COPE Clinic