Physiology of the Weight Reduced State (POWERS)
POWERS - Understanding Body Changes After Weight Loss
Sponsor: NIH and NIDDK
Enrolling: Male and Female Patients
Study Length: 18 Months
IRB Number: AAAU4666
U.S. Govt. ID: NCT05748158
Contact: Michelle Horowitz: 646-317-1435 /
Additional Study Information: The Physiology of the Weight Reduced State (POWERS) is a national research study designed to discover and learn what happens to the human body after weight loss and to learn why some people regain their lost weight. Understanding why this happens could help health professionals improve strategies for successful weight loss maintenance after weight loss. POWERS is a research study with a goal to understand the changes in the body that occur after weight loss and learn how these changes affect the ability to keep the weight off. It involves universities, medical centers, researchers, and most importantly, study participants. Learning about how the body changes with weight loss will help researchers and clinicians to better guide people on weight loss programs in the future. POWERS is supported and managed by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) at the National Institutes of Health (NIH). For more information, go to
Rudolph Leibel, MD
Do You Qualify?
Are you between 25 and 59 years old? Yes No
Do you have obesity (BMI between 30-40 kg/m2)? Yes No
Do you have Type 1 or Type 2 Diabetes or taking a glucose lowering medication? Yes No
Do you take medications that affect appetite or weight (e.g. appetite suppressants, inhaled steroids, alpha or beta-blockers)? Yes No
Are you able to participate in a cycling test? Yes No
You may be eligible for this study

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For more information, please contact:
Michelle Horowitz